Prospective Randomized Study Comparing Sentinel Lymph Node Evaluation With Standard Pathologic Evaluation for the Staging of Colon Carcinoma: Results From the United States Military Cancer Institute Clinical Trials Group Study GI-01

摘要

One hundred sixty-one patients with stage I–III colon cancer were assigned randomly to standard histopathologic evaluation or sentinel lymph node mapping and ultrastaging with pan-cytokeratin IHC in conjunction with standard histopathology. Targeted nodal assessment identified small volume nodal disease and improved staging in patients with resectable colon cancer.